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Stem Cell Research
GA 2001

Stem cell research

A big issue today -- but the PC(USA) has already done good thinking on the questions 

[7-25-01]

Witherspoon's GA wrap-up report included this brief reference to the Assembly's action on stem cell and fetal tissue research:

The Assembly approved a carefully crafted Statement on the Ethical and Moral Implications of Stem Cell and Fetal Tissue Research, sent as an overture from Baltimore Presbytery. Recognizing the progress in stem cell and fetal tissue research and the complexity of the moral issues involved, the proposed guidelines offer guidance on the use of tissue derived from fetuses, separating the decision to have an abortion from the decision to donate fetal tissue. Sale or commercialization of fetal tissue should be legally prohibited; research with stem cells obtained from human embryos should be conducted only when the goals are compelling and unreachable by other means.

Since the Administration is currently considering various options for government support of this vital and promising -- and controversial -- research, it may be worth looking at the full text of the action taken by the 213th General Assembly.

It is also available on the PC(USA) web site.




Overture 01-50. On Adopting a Resolution Enunciating Ethical Guidelines for Fetal Tissue and Stem Cell Research-From the Presbytery of Baltimore.

((((()))))


The Presbytery of Baltimore overtures the 213th General Assembly (2001) to approve the following resolution in accordance the General Assembly Guidelines "Forming Social Policy" paragraph 4:

Whereas, the following policy statements of previous General Assemblies of the Presbyterian Church (U.S.A.) provide general guidance that may be considered to apply to fetal tissue and stem cell research:

1. "The Covenant of Life and the Caring Community" (1983), which states, "The 195th General Assembly (1983): . . . Discourages development of human embryos and their use for experimentation except in those cases of clearly demonstrable benefit where no other substitute could accomplish the same end" (Minutes, 1983, Part I, p. 364). The statement goes on to state, "As society looks to the benefits of biotechnology, there must be more serious social and ethical discussion about its application, especially human application. Abuses in eugenics programs in the recent past make the establishment of guidelines for the application of biotechnologies to human beings mandatory. The deepest issues of life and its meaning must not be obscured in the rush to profits and benefits promised by new biotechnologies." [Ibid., p. 365]

2. "Do Justice, Love Mercy, Walk Humbly" (1992), which included the following response to Commissioners' Resolution 89-33 from the 207th General Assembly (1989): "The [General Assembly] concurs with the intent of the resolution to oppose abortions for the express purpose of selling or providing tissues for research or transplantation, and is opposed to the sale of fetal human tissue obtained in elective abortion. However, we are opposed to, and cannot concur with, calling on Congress to prohibit the use of federal funding for research using fetal tissue" (Minutes, 1992, Part I, p. 373); and

Whereas, since these statements were made, both the possible benefits of, and the complicated moral issues involved with, stem cell and fetal tissue research have greatly increased and demand the specific attention of Presbyterians and the larger society; therefore, be it

Resolved, That the 213th General Assembly (2001) of the Presbyterian Church (U.S.A.) approves for itself, commends to governing bodies and individual Presbyterians, and presents to the larger society for its consideration the following "Statement on the Ethical and Moral Implications of Stem Cell and Fetal Tissue Research":

Introduction

Contemporary medical research and technologies have presented humankind with complex ethical and moral realities never before envisioned. These realities bear careful review and consideration as new therapies are developed to cure diseases and illnesses. As people of faith we are called to be partners with God in healing and in the alleviation of human pain and suffering.

Human pluripotent stem cells, more commonly known simply as stem cells, are derived through two different methods: one uses early stage embryos in excess of clinical need and donated by women undergoing in vitro fertilization; the other method isolates stem cells from aborted fetuses. Stem cells have the ability to divide for an indefinite period in culture and can develop into most of the specialized cells and tissues of the body, such as muscle cells, nerve cells, liver cells, and blood cells. The use of stem cells has far-reaching possibilities including "cell therapies." Stem cells stimulated to develop into specialized cells could be used to treat diseases such as Parkinson's, Alzheimer's, spinal cord injuries, stroke, burns, heart disease, and diabetes. Using stem cells could reduce the dependence on organ donation and transplantation.

The moral issues raised by stem cell research differ, depending on whether the cells come from aborted fetuses or embryos resulting from in vitro fertilization that are no longer needed for infertility treatment.

Research on Tissue Resulting from Abortion

The ethical acceptability of deriving stem cells from the tissue of aborted fetuses is closely connected to the morality of abortion. Those who oppose using stem cells derived from aborted fetuses argue that abortion for any reason is wrong. Those who so believe also fear that the possibility of donating the fetus for stem cell research will encourage women to have more abortions or justify abortions that otherwise could not be justified. They believe that researchers would be complicit in an immoral act. In addition, they may believe that a woman seeking an abortion should not have the right to give consent to the use of the tissue because she has forfeited her maternal trusteeship by aborting the fetus.

The General Assemblies of the Presbyterian Church (U.S.A.) have consistently supported women's right to choose an abortion based on conscience and religious beliefs. We believe that a woman's right to evaluate her life situation and the impact of her pregnancy on her own health and on her obligations to other family members is an essential element of her personhood and her status as a moral being. We view abortion as not only protected under U.S. law, but as morally justifiable in certain circumstances.

We believe that the use of tissue derived from fetuses is morally and ethically acceptable, provided that the procurement of that tissue is subject to appropriate limitations, and we believe that such limitations should be incorporated into regulatory law. Regulation of donations needs to assure that the decision to have an abortion is separated from the decision to donate fetal tissue. The sale or commercialization of fetal tissue should be legally prohibited.

Research with Stem Cells Derived from Embryos

Research with stem cells obtained from human embryos poses moral difficulties that do not exist in the case of fetal tissues. The life of the fetus has already been terminated when the researcher receives tissue from an aborted fetus, while the life of embryonic tissue resulting from infertility treatment must be terminated. The morality of ending the life of embryos rests on how one views the moral status of the embryos. We believe, as do most authorities that have addressed the issue, that human embryos do have the potential of personhood, and as such they deserve respect. That respect must be shown by requiring that the interests or goals to be accomplished by using human embryos be compelling and unreachable by other means. Indications are that human embryonic stem cell research has the potential to lead to lifesaving breakthroughs in major diseases. Currently, this knowledge cannot be obtained from cells derived from other sources such as adult stem cells and cadaveric fetal tissue. Prohibition of the derivation of stem cells from embryos would elevate the showing of respect to human embryos above that of helping persons whose pain and suffering might be alleviated. Embryos resulting from infertility treatment to be used for such research must be limited to those embryos that do not have a chance of growing into personhood because the woman has decided to discontinue further treatments and they are not available for donation to another woman for personal or medical reasons, or because a donor is not available. Again, the sale or commercialization of embryonic tissue should be legally prohibited.

Conclusion

Therefore, the 213th General Assembly (2001) of the Presbyterian Church (U.S.A.), affirms the use of fetal tissue and embryonic tissue for vital research. Our respect for life includes respect for the embryo and fetus, and we affirm that decisions about embryos and fetuses need to be made with responsibility. Therefore, we believe that the Presbyterian Church (U.S.A.) and other faith groups should educate their members in making these very difficult ethical decisions. With careful regulation, we affirm the use of human stem cell tissue for research that may result in the restoring of health to those suffering from serious illness. We affirm our support for stem cell research, recognizing that this research moves to a new and challenging frontier. We recognize the need for continuing, informed public dialogue and equitable sharing of information of the results of stem cell research. It is only with such public dialogue and information sharing that our diverse society can build a foundation for responsible movement toward this frontier that offers enormous hope and challenge.

Rationale

The present political climate, especially with the change of national administrations, suggests that we may see serious attempts to limit or eliminate fetal tissue and stem cell research.

While the General Assembly has previously opposed the commercialization of fetal tissue and the creation of embryos for research purposes, it has not directly addressed the specific research issues addressed here, though the conclusions stated here can logically be derived from existing policy statements.

The ethical and medical issues are specifically addressed in the resolution.

The proposed statement is based in part on a similar statement adopted by the Board of Directors of the Religious Coalition for Reproduction Choice, August 24, 2000.


((((()))))


ACSWP ADVICE AND COUNSEL ON OVERTURE 01-50

Advice and Counsel on Overture 01-50----From the Advisory Committee on Social Witness Policy (ACSWP).

Overture 01-50 proposes approving a resolution that enunciates ethical guidelines for fetal tissue and stem cell research, building on previous General Assembly policies.

The Advisory Committee on Social Witness Policy advises that the Overture 01-50 is consistent with previous General Assembly policies.

Rationale: Overture 01-50 is proposed to General Assembly in the form of a resolution. A resolution "applies existing policy statements to new circumstances" ("Why and How the Church Makes a Social Policy Witness," Minutes,1993, Part I, p. 768). The development of a resolution requires that there is adequate policy so that policy can be applied to current societal realities.

This resolution accurately builds on policies of past General Assemblies. The second "Whereas" refers to: "Abortion is not morally acceptable for gender selection only or solely to obtain fetal parts for transplantation" (Minutes, 1992, Part I, p. 368). An additional statement, made in response to Commissioners' Resolution 89-33 (Minutes, 1992, Part I, p. 373), is accurately quoted in Overture 01-50..

The 195th General Assembly (1983) stated that it "Discourages development of human embryos and their use for experimentation except in those cases of clearly demonstrable benefit where no other substitute could accomplish the same end" (Minutes, 1983, Part I, p. 361). The overture includes another direct quote from the 195th General Assembly (1983) that declares the need for establishing guidelines for this work (Minutes, 1983, Part I, p. 365). Overture 01-50 proposes one step in developing those guidelines.

Stem cell research continues to develop very rapidly. A lot of research is underway using cells from umbilical cords and adult cell types. Highly promising and significant progress is reported weekly. However, at this time and in the near future, most of the stem cells will continue to be derived from early stage embryos and aborted fetuses. Therefore, scientists believe that all avenues of research should remain open.

 

 
 

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